The effect of Atherogenicity index in Type 2 Diabetes mellitus patients and it is association with chronic cardiovascular complications of the disease

Abstract

Atherosclerotic cardiac disease (ASCVD) is a significant health issues among people who have Type 2 diabetes mellitus (T2DM). Diabetic patients experience ASCVD-related consequences 14.6 years faster than non-diabetic individuals. The main goal of the study was to assess the relevance of the atherogenic index of plasma (AIP) and other lipid-related indicators in predicting ASCVD risk in Iraqi T2DM patients.

Material and method: The Diabetes Research Centre at Mustansiriyah University in Baghdad compared 50 individuals with T2DM (25 males and 25 females) to 50 healthy controls. We measured anthropometrics, fasting blood sugar (FBS), HbA1c, and lipid profiles

Results: T2DM patients had significantly greater levels of FBS, HbA1c, TC, TG, LDL, and VLDL, as well as lower levels of HDL than controls (p < 0.001). AIP, computed as log(TG/HDL), was likewise raised in diabetes individuals. Female T2DM patients had greater FBS and HbA1c values than males. Patients and controls showed significant disparities in anthropometric measurements, including waist-to-hip ratio (WHR) (p < 0.001). Conclusion: These documented results show the crucial impact of AIP and lipid profiles in determining cardiovascular risk in T2DM patients, emphasizing the importance of early intervention and management measures in this high-risk population.