Association of Vitamin D and B12 in Glycemic status among Iraqi Patients with Type 2 Diabetes

Abstract

The purpose of this study was to assess the correlation between vitamin D, vitamin B12, and glycemic control (HbA1c) in individuals with type 2 diabetes. For this investigation, a total of seventy volunteers were enlisted. Standard biochemical techniques were used to assess serum levels of vitamin D, vitamin B12, and HbA1c, and SPSS was used for statistical analysis. The average vitamin B12 level was 363.89 ± 122.17 ng/mL, the average vitamin D concentration was 26.64 ± 12.12 ng/mL, and the average HbA1c level was 5.32 ± 0.81%. Vitamin D and HbA1c showed a weak negative connection (r = -0.28, p = 0.048), indicating that lower vitamin D levels might be linked to worse glycemic management. HbA1c and vitamin B12 (p = 0.75) and vitamin D and vitamin B12 (p = 0.86) did not significantly correlate. The findings indicate that Vit-D may play a minor but significant role in glucose regulation, whereas Vit-B12 appears to have no direct influence on glycemic status in this cohort. Further studies with increased sample magnitude recommended to substantiate these preliminary data.