Revealing the Urinary Microbiota in Prostate Cancer: A Comprehensive Review Unveiling Insights into Pathogenesis and Clinical Application

Abstract

Prostate cancer is one of the most common malignancies and seriously affects public health. Recently, contemporary microbiome research has found hints that the urinary microflora may at least to some extent impact prostate cancer formation and treatment outcomes. A comprehensive review This article attempts to provide a brief summary and integration of the current knowledge about involvement in prostate cancer development by urinary microbiota, diagnostic capabilities, as well as therapeutic opportunities.It examines the different microbial spheres found inside residents in the genitourinary system and their relevance to tumorigenic microenvironments. The review looks at microbial signatures linked to prostate cancer, and tries to identify potential biological markers for diagnosis of the disease or patient stratification according to risk levels, as well as potential predictors of outcome. Secondly, the potential effect of urine microbiota upon treatment response and how to design novel therapeutic interventions also form key topics in this study.After a comprehensive review of existing literature and recent new studies, this article attempts to illuminate the intricate interrelationships between urinary microbiota and prostate cancer. It is hoped that this effort will provide some insight on future directions of research, clinical applications and even possibilities for precision-medicine paradigms in prostate cancer care.